Figure 1.

A 67-year-old man with advanced gastric cancer of the lesser curvature who underwent contrast enhanced CT pre (A) and post (B) NAC. Although the post-NAC CT clearly shows a reduction in the size of tumoral mass, delta parameters (entropy, GLCM-contrast, GLCM-entropy, GLCM-dissimilarity) classify this patient as non-responder. The finding is confirmed on final histopathology after surgery (adenocarcinoma ypT3, tumor regression grade 3 according to Becker et al.). NAC, neoadjuvant chemotherapy; CT, computed tomography; GLCM, grey-level co-occurrence matrix.