Table 2.
Biological process gene ontology (GO) terms of calcium-related differentially expressed genes (DEGs) during myotube differentiation in QM7 cells
| GO term | Gene count | Gene symbol |
|---|---|---|
| Calcium channel complex | 10 | CASQ2, CAV3, CACNA1S, CACNA2D1, CACNA1B, CACNA1D, ANXA5, PDE4B, CACNG3, CACNB4 |
| Calcium channel activity | 8 | CAV3, CACNA1S, CACNA1B, CACNA1D, RASA3, TRPV1, SLC24A2, CACNB4 |
| Calcium mediated signaling | 15 | CASQ2, PLN, ATP2A2, CLIC2, HDAC4, CACNA1D, RCAN3, TOX3, SLC9A1, LRRK2, KDR, ATP1B1, TPCN3, TRPV1, GSTO1 |
| Calcium ion binding | 16 | MYL1, MYL3, TNNC1, CHIA, NELL2, DAG1, CAPN1, CDH2, VLDLR, CANX, CIB1, MYL9, ANXA2, EFHD1, SPTAN1, FBLN5 |
| Calcium ion import | 11 | CACNA2D1, ATP2A2, WNT5B, FKBP1A, CACNA1D, RASA3, CHERP, ANXA2, VDAC2, TPCN3, TRPV1 |
| Calcium ion homeostasis | 29 | CASQ2, PLN, CAV3, GRIA1, BOK, SLC8A3, SMAD3, ATP2A2, STIM1, ATP2B1, F2, HCRTR2, CRY2, FKBP1A, RASA3, CHERP, PTH1R, VAPB, CD24, ATP1B1, GNB1, ANXA7, ATP13A2, GALR2, F2RL1, TPCN3, TRPV1, SLC24A2, CACNB4 |
| Response to calcium | 22 | CASQ2, TNNT2, CAPN3, SPARC, CPNE2, STIM1, DUSP1, ENTPD6, ANXA11, ANXA5, IL6, SEC31A, ANXA7, KCNIP2, PPP2CA, CCND1, WNT5A, ALOX5AP, PPIF, RANBP1, SLC25A13, INHBB |
| Calcium ion export | 2 | SLC8A3, ATP2B1 |
| Detection of calcium | 3 | CASQ2, STIM1, KCNIP2 |