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. 2018 Aug 30;8:356. doi: 10.3389/fonc.2018.00356

Figure 2.

Figure 2

In vivo P2Et treatment delays melanoma and breast tumor growth, but this effect is lost when P2Et pretreatment is also provided. (A) B16F10 individual tumor volumes for all groups. (B) B16F10 tumor growth curve. (C) 4T1 individual tumor volumes for all groups. (D) 4T1 tumor growth curve. (E) 4T1 frequency of metastasis among the different groups. (F) Distribution of multi-organ metastasis of 4T1 tumors for all groups. n corresponds to the number of mice with metastases. In all cases, data are represented as the mean ± SEM. The p values were calculated using a Mann-Whitney U test. *p < 0.05, **p < 0.01.