Figure 7.

Poly(ethylene glycol)-Based Hydrogel Designed to Encapsulate Islets Shows Vascular Remodeling in the Omentum with Vasculogenic Layer

(A) Schematic for synthetic hydrogel macroencapsulation device design. A non-degradable synthetic hydrogel disk is surrounded by a degradable, vasculogenic hydrogel that remodels to promote device vascularization post-transplantation. (B–D) Surface vascularization was characterized and quantified for number of (B) vessel junctions and branches, (C) average and maximum branch length, and (D) total overall vessel length per field of view (FOV) (n = 4/condition; FOV = 5–8/n). *p < 0.05; **p < 0.005.¹⁰⁵ Error bars, SEM.