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Table 1.

Cell Delivery Applications in Natural and Synthetic Hydrogels

Hydrogel Material(s) Cells Delivered Delivery Strategy Target Application Ref.
Encapsulated hydrogels alginate pancreatic islets laparoscopic implant of microcapsules diabetes 184
adipose-derived and mesenchymal stem cells injection co-delivered with BMP-2 bone regeneration 185
CAR-programmed T cells implanted into the peritoneal or tumor resection cavity cancer 186
polyethylene glycol and alginate ovarian follicles encapsulated scaffold ovarian function 177
Tissue-integrating microporous hydrogels gelatin adipose-derived stromal cells microporous microribbon hydrogel injected into cranial defect bone regeneration 76
collagen autogenous chondrocytes porous scaffold matrix cartilage repair 82
alginate mesenchymal stem cells injectable, void-forming microporous hydrogel bone regeneration 178
Biodegradable hydrogels collagen iPSC-derived hepatocytes and endothelial cells encapsulated polyelectrolyte fiber scaffold transplanted into liver liver tissue regeneration 180
neonatal astroglial cells transplanted gel into lesion of spinal cord spinal cord regeneration 181
hyaluronic acid cardiac progenitor cells subcutaneous injection angiogenesis 182
neural progenitor cells injection into stroke cavity neural regeneration from stroke 183
gelatin cardiac-derived stem cells intra-myocardial injection with the controlled release of bFGF cardiac regeneration 172
polyethylene glycol with degradable peptide crosslinker adipose-derived stem cells in situ injection with encapsulated siRNA bone regeneration 160
iPSC-derived endothelial cells injection co-delivered with VEGF muscle repair 173
fibronectin and agarose cardiac stem cells in situ injection cardiac regeneration 174
fibrin human embryonic stem cells epicardial delivery of encapsulating gel cardiac regeneration 175
adipose-derived mesenchymal stromal cells patch applied to surface of skin wound healing 187