Table 1.

Side effect profiles of selected antipsychotic drugs

Adverse effects	AMI	ARI	CPZ	CLO	HAL	LUR	OLA	PAL	PER	QUE	RIS	SER	ZIP
Anticholinergic effects	0	0	++	+++	0	0	++	0	0/+	+/++	0	0	0
Acute parkinsonism	+	+	+	0	+++	+/++	0/+	++	++	0	++	0/+	+
Akathisia	+	++	+	+	+++	+/++	+	+	++	+	+	+	+/++
Tardive dyskinesia	0/+	0/+	++	0	++	0/+	0/+	0/+	++	0/+	0/+	0/+	0/+
Diabetes	0/+	0/+	+++	+++	0/+	0/+	+++	+	+	++	+	+	0/+
Weight gain	0/+	0/+	+++	+++	+	0/+	+++	++	++	++	++	++	0/+
Increased lipids	+	0/+	+++	++	0/+	0/+	+++	+	+	++	+	+	0/+
Sialorrhea	0	0	0	++	0	0	0	0	0	0	0	0	0
Neutropenia	0/+	0/+	0/+	+++	0/+	0/+	0/+	0/+	0/+	0/+	0/+	0/+	0/+
Orthostatic hypotension	0/+	0/+	++	++	0	0/+	+	+	+	++	+	++	0
Hyperprolactinemia	+++	0	+	+	++	+	+	+++	++	0	+++	+	+
Increased QTc interval	++	0/+	0/+	++	0+	0/+	0/+	+	+	+	+	++/+++	++
Sedation	0/+	0/+	++	+++	+	+/++	+/++	0/+	+	++ b	+	0/+	+
Seizures	0/+	0/+	0/+	++	0/+	0/+	0/+	0/+	0/+	0/+	0/+	0/+	0/+

AMI – amisulpride, ARI – aripiprazole, CPZ – chlorpromazine, CLO – clozapine, HAL – haloperidol, LUR – lurasidone, OLA – olanzapine, PAL – paliperidone, PER – perphenazine, QUE – quetiapine, RIS – risperidone, SER – sertindole, ZIP – ziprasidone, 0: none or equivocal, 0/+: minimal/rare, +: mild/sometimes occurs, ++: moderate/occurs frequently, +++: severe/occurs very often