Table 3.
Multivariate Cox proportional hazard analysis for predictors of foot disorders in the diabetes cohort.
| Predictor | Unadjusted HR (95% CI) | p-value | Adjusted HR (95% CI) | p-value |
|---|---|---|---|---|
| Gender | ||||
| Male | 6.93 (3.11–8.00) | <0.001 | 2.51 (1.88–4.23) | <0.001 |
| Female | 1 | |||
| Duration of diabetes | ||||
| A 5-year increase | 3.40 (2.92–3.99) | <0.001 | 2.36 (1.21–3.16) | 0.008 |
| Type of diabetes | ||||
| Type 1 | 1 | |||
| Type 2 | 1.20 (0.8–2.13) | 0.17 | ||
| Body mass index | ||||
| Each 5-kg/m2 increase | 5.3 (3.11–8.96) | <0.001 | 3.2 (2.51–7.25) | <0.001 |
| Glycaemic control | ||||
| A percentage increase in HbA1c | 1.23 (1.08–1.42) | 0.003 | 1.11 (1.05–1.25) | 0.03 |
| Dyslipidaemia | ||||
| Present | 0.84 (0.51–1.36) | 0.47 | – | – |
| Absent | 1 | |||
| Hypertension | 2.51 (1.02–1.71) | <0.001 | 1.14 (1.12–3.21) | <0.001 |
| Nephropathy | 5.6 (2.3–8.3) | 0.07 | 2.15(1.92–3.21) | 0.002 |
| Lipid therapy | 1.02 (0.67–1.32) | 0.13 | – | – |
| Antiplatelet therapy | 0.56 (0.12–1.12) | 0.23 | – | – |
| Previous foot disorders | 7.32 (4.31–12.34) | <0.001 | 3.24 (2.12–7.12) | 0.001 |
CI: confidence interval; HR: hazard ratio.