Table 4.

Effect of increased inclusions of a Saccharomyces cerevisiae fermentation product (SCFP) on blood components, serum IL-8, and serum haptoglobin of newly weaned beef steers following a Mannheimia haemolytica vaccination¹

	Treatment2			SEM	P-value
	CON	SCFP14	SCFP28		CON vs. SCFP14	SCFP14 vs. SCFP28	Day4
Blood component5
WBC, 103/µL	12.1	12.1	11.9	0.30	0.94	0.62	0.01
RBC, 106/µL	9.4	9.4	9.4	0.07	0.81	0.99	0.07
Hemoglobin, g/dL	13.4	13.3	13.4	0.11	0.45	0.50	0.01
Hematocrit, %	37.2	36.9	37.4	0.34	0.52	0.26	0.01
Platelets, 103/µL	499	575	531	34.3	0.11	0.34	0.36
Neutrophils, 103/µL	4.0	4.0	4.0	0.22	0.94	0.94	0.01
Eosinophils, 103/µL	0.2	0.2	0.2	0.02	0.86	0.25	0.06
Basophils, 103/µL	0.1	0.1	0.1	0.01	0.59	0.17	0.03
Lymphocytes, 103/µL	6.9	7.0	6.8	0.19	0.63	0.55	0.01
Monocytes, 103/µL	0.7	0.7	0.7	0.02	0.83	0.90	0.01
Serum
IL-8, pg/mL	255	218	295	35.4	0.35	0.08	0.01
Haptoglobin, mg/dL	14.7	13.9	17.9	1.71	0.67	0.07	0.01

¹Vaccination given on day 34. Blood samples from days 3, 6, 9, 11, and 14 post vaccination. Data from blood samples taken prior to vaccination used as a covariate in analysis.

²CON = Original XPC (Diamond V, Cedar Rapids, IA) at 0 g·steer⁻¹·d⁻¹; SCFP14 = Original XPC at 14 g·steer⁻¹·d⁻¹; SCFP28 = Original XPC at 28 g·steer⁻¹·d⁻¹.

³Highest SEM of any treatment reported.

⁴Based on repeated measures analysis; treatment × day P ≥ 0.28 for all variables.

⁵WBC = white blood cells; RBC = red blood cells; WBC, neutrophils, eosinophils, monocytes, IL-8, and haptoglobin natural log transformed; back-transformed means and SEM presented.