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. 2018 Jun 22;26(9):2255–2266. doi: 10.1016/j.ymthe.2018.06.016

Figure 3.

Figure 3

A Combination of AA and NG Largely Enhances Cytotoxic NK Cells Infiltrating the LLC Tumor Microenvironment

(A) Two-color immunofluorescence shows that numbers of cytotoxic NK cells (NK1.1+NKp46+ cells) in the LLC tumor microenvironment are largely increased in mice with the combination of AA and NG when compared to individual treatment. NK1.1, green; NKp46, red; DAPI, blue. (B) Two-color flow cytometry detects that numbers of cytotoxic NK cells (NK1.1+NKp46+ cells) in peripheral blood of LLC tumor-bearing mice are largely increased in mice with the combination of AA and NG when compared to individual treatment. Each bar represents the mean ± SEM for groups of three mice; *p < 0.05, **p < 0.01, and ***p < 0.001 compared to control; ##p < 0.01 and ###p < 0.001 as indicated. Scale bars, 100 μm.