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. 2018 Sep 7;6:88. doi: 10.1186/s40478-018-0592-3

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© The Author(s). 2018

Open AccessThis article is distributed under the terms of the Creative Commons Attribution 4.0 International License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Fig. 1 — Expression of inflammatory molecules in the presence of systemic infection in Alzheimer’s disease using quantitative real-time PCR. The levels of indicated transcripts are normalised to GAPDH, and the mRNA Alzheimer’s disease without systemic infection (AD-) levels are arbitrary set as 1. The bar graph shows the fold difference in mRNA of inflammatory markers and indicates significant increased anti-inflammatory gene transcripts CHI3L1 (p = 0.012) and IL4R (p = 0.04) in Alzheimer’s disease with (AD+) compared to without systemic infection (AD-)