Table 3.
Types of medication changes between baseline and 9 months, intervention vs. control group
| Types of medication change | Intervention N = 622 Mean # of changes (% of total)a |
Control N = 596 Mean # of changes (% of total)a |
Adjusted differenceb | p value |
|---|---|---|---|---|
| Medication additions | 1.79 (44%) | 1.51 (42%) | 2% | 0.37 |
| Medication discontinuations | 1.70 (42%) | 1.63 (45%) | 3% | 0.09 |
| Therapeutic substitutions | 0.15 (4%) | 0.15 (4%) | 0% | 0.91 |
| Dose increases | 0.18 (5%) | 0.19 (6%) | 1% | 0.39 |
| Dose reductions | 0.21 (6%) | 0.15 (4%) | 2% | 0.007 |
| TOTAL NUMBER OF CHANGES | 4.04 (100%) | 3.62 (100%) | – | – |
a Results show the mean number of each type of medication change within each group, and the percent of all changes attributable to each type of change
b Difference between intervention and control group in the percent of changes attributable to each type of change. Adjusted for baseline subject characteristics and clustering