Table 3.
Univariable and multivariable Cox regressions for overall survival
| Univariable |
Multivariable |
|||
|---|---|---|---|---|
| HR (95% CI) | P-value | HR (95% CI) | P-value | |
| Age | 1.08 (1.05-1.11) | < .001 | 1.07 (1.04-1.11) | < .001 |
| Sex | ||||
| Male | 1 | 1 | ||
| Female | 0.29 (0.15-0.56) | < .001 | 0.44 (0.22-0.88) | .019 |
| Tumor size | ||||
| ≤3 cm | 1 | 1 | ||
| 3-5 cm | 3.28 (0.75-14.35) | .115 | 3.14 (0.71-13.85) | .132 |
| >5 cm | 4.30 (1.02-18.18) | .048 | 2.85 (0.66-12.24) | .160 |
| Charlson Deyo cormobidity score | ||||
| 0 | 1 | 1 | ||
| 1 | 2.13 (1.06-4.29) | .035 | 1.42 (0.69-2.91) | .345 |
| ≥2 | 1.26 (0.38-4.15) | .705 | 0.75 (0.22-2.50) | .638 |
| Race | ||||
| White | 1 | — | — | |
| Nonwhite | 1.00 (0.46-2.17) | 1.000 | — | — |
| WHO grade | ||||
| I | 1 | 1 | ||
| II | 1.98 (0.97-4.03) | .061 | 0.75 (0.30-1.87) | .538 |
| Surgery | ||||
| STR | 1 | 1 | ||
| GTR | 2.08 (1.11-3.91) | .022 | 1.62 (0.73-3.60) | .237 |
| Resection, NOS | 1.81 (0.42-7.83) | .425 | 2.12 (0.47-9.50) | .328 |
| Facility type | ||||
| Nonacademic | 1 | — | — | |
| Academic | 0.66 (0.35-1.23) | .190 | — | — |
| RT Modality | ||||
| EBRT | 1 | 1 | ||
| SRS/HF-SRS | 0.21 (0.05-0.88) | .032 | 0.24 (0.06-1.03) | .055 |
CI, confidence interval; EBRT, external beam radiation therapy; GTR, gross total resection; HF- HR, hazard ratio; NOS, not otherwise specified; RT, radiation therapy; SRS, hypofractionated stereotactic radiation surgery; SRS, stereotactic radiation surgery; STR, subtotal resection; WHO, World Health Organization.