Fig. 1.

Artesunate accumulates in the mitochondria. (A) Chemical structures of artemisinin and artesunate (ART). (B) Fluorescence microscopy for the localization of ART in HeLa cells. The cells were treated with red fluorescent ART (20 µM) for 30 min and then immunostained with anti-translocase Of Outer Mitochondrial Membrane 20 (TOMM20) and green fluorescence dye. All images were analyzed using confocal microscopy. Scale bar: 10 µm.