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. Author manuscript; available in PMC: 2018 Sep 7.
Published in final edited form as: Mod Pathol. 2017 Aug 4;30(12):1655–1665. doi: 10.1038/modpathol.2017.98

Table 1.

Summary of clinical and pathological features of the studied oral cavity squamous cell carcinoma cohorts

Entire cohort N (%) Modeling set N (%) Test set N (%) P-value
No. of patients 115 50 65
Age 61.0 ± 12.0 62.9 ± 13.3 59.5 ± 10.7 0.1545
Sex 0.0006
 Female 63 (54.8) 18 (36.0) 45 (69.2)
 male 52 (45.2) 32 (64.0) 20 (30.7)
Race 0.8530
 White 54 (47.0) 24 (48.0) 30 (46.2)
 Other 61 (53.0) 26 (52.0) 35 (53.8)
Smoking 1
 Ever 29 (90.6) 16 (94.1) 13 (86.7)
 Never 3 (9.4) 1 (5.9) 2 (13.3)
Comorbidity score 0.8263
 None/mild 59 (64.8) 26 (52.0) 33 (50.8)
 Moderate/severe 32 (35.2) 13 (26.0) 19 (29.2)
Treatment 0.1494
 Surgery only 33 (29.7) 11 (22.0) 22 (33.9)
 Postoperative or definitive 78 (70.3) 38 (76.0) 40 (61.5)
Pathology histology 0.8262
 Well/moderately differentiated 88 (76.5) 39 (78.0) 49 (75.4)
 Poorly differentiated 27 (23.5) 11 (22.0) 16 (24.6)
N-stage 0.5492
 N0/N1 75 (66.4) 35 (70.0) 40 (61.5)
 N2 38 (33.6) 15 (30.0) 23 (35.4)
N-stage 0.7055
 N0 55 (48.7) 23 (46.0) 32 (50.8)
 N1/N2 58 (51.3) 27 (54.0) 31 (49.2)
T-stage 0.3433
 T1/T2 64 (57.1) 26 (52.0) 38 (58.5)
 T3/T4 48 (42.9) 24 (48.0) 24 (36.9)
Margin 0.4762
 Negative 91 (80.5) 37 (74.0) 54 (83.1)
 Positive 22 (19.5) 11 (22.0) 11 (16.9)
Chemotherapy 0.2321
 No 78(67.0) 34 (68.0) 44 (67.7)
 Yes 22 (33.0) 13 (26.0) 9 (13.9)
Patient status 0.2577
 Alive 69 (60.0) 27 (54.0) 42 (64.6)
 Dead 46 (40.0) 23 (46.0) 23 (35.4)
Disease recurrence 0.1330
 No 85 (73.9) 33 (66.0) 52 (80.0)
 Yes 30 (26.1) 17 (34.0) 52 (80.0)

Value in bold is statistically significantly different between the Modeling and Test sets, P < 0.05.