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. Author manuscript; available in PMC: 2018 Sep 7.
Published in final edited form as: Mod Pathol. 2017 Aug 4;30(12):1655–1665. doi: 10.1038/modpathol.2017.98

Table 2.

Performance of four different classifiers with three different feature selection methods in the modeling set

Classifier Feature selection AUC Accuracy Specificity Sensitivity
LDA WRST 0.74 ± 0.07 0.83 ± 0.03 0.91 ± 0.10 0.67 ± 0.04
MRMR 0.83 ± 0.05 0.79 ± 0.07 0.87 ± 0.08 0.65 ± 0.09
RF 0.77 ± 0.05 0.81 ± 0.03 0.91 ± 0.10 0.62 ± 0.06
QDA WRST 0.87 ± 0.02 0.88 ± 0.02 0.93 ± 0.10 0.78 ± 0.04
MRMR 0.81 ± 0.04 0.84 ± 0.05 0.88 ± 0.14 0.76 ± 0.04
RF 0.83 ± 0.06 0.85 ± 0.3 0.91 ± 0.15 0.72 ± 0.06
RF WRST 0.81 ± 0.05 0.77 ±0.04 0.87 ± 0.06 0.59 ± 0.02
MRMR 0.84 ± 0.03 0.81 ±0.04 0.87 ± 0.06 0.68 ± 0.06
RF 0.78 ± 0.04 0.74 ± 0.04 0.83 ± 0.13 0.58 ± 0.05
SVM WRST 0.86 ± 0.02 0.82 ± 0.03 0.93 ± 0.06 0.62 ± 0.04
MRMR 0.79 ± 0.07 0.72 ± 0.04 0.90 ± 0.15 0.35 ± 0.06
RF 0.84 ± 0.02 0.79 ± 0.02 0.92 ± 0.08 0.53 ± 0.03

Abbreviations: AUC, area under curve; LDA/QDA, linear/quadratic discriminant analysis; MRMR, minimum redundancy, maximum relevance feature selection method; RF, random forest; SVM, support vector machine; WRST, Wilcoxon rank sum test.

The best performance in each metric/column is shown in bold.