Table 4.

Univariate log-rank analysis for disease-specific survival on the test set including OHbIC (n = 65 patients)

Variable	Disease-specific survival HR (95% CI)	P-value
Age ≤60 vs >60	0.39 (0.12–1.26)	0.103
Race Nonwhite vs white	0.80 (0.20–3.26)	0.7435
PaQi histology Well/moderately differentiated vs poorly differentiated	1.93 (0.59–6.29)	0.3006
T-stage T1/T2 vs T3/T4	2.62 (0.86–8.03)	0.0855
N-stage N0 vs N1/N2	1.66 (0.89–3.08)	0.1088
N-stage N0/N1 vs N2	2.14 (0.69–6.61)	0.1771
Comorbidity score Non/mild vs moderate/severe	3.02 (0.80–11.45)	0.1047
Overall stage I/II vs III/IV	3.71 (0.82–16.80)	0.0519
Chemotherapy Yes vs no	1.96 (0.40–9.66)	0.4359
Treatment Surgery only vs postoperative/definitive	1.75 (0.47–6.48)	0.3830
OHbIC Positive vs neeative	3.31 (1.08–10.14)	0.0335

Abbreviations: CI, confidence interval; HR, hazard ratio; OHbIC, oral cavity squamous cell carcinoma quantitative histomorphometric-based image classifier.

Value in bold is statistically significant, P < 0.05..