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. 2018 Aug 30;24:6044–6052. doi: 10.12659/MSM.908529

Figure 1.

Figure 1

NLRP3 inflammasome-mediated pyroptosis contributed to cardiomyocyte loss following MI. SD rats of sham group or MI group were sacrificed 7 d after surgery. (A) Representative images of HE staining of rat heart in sham and MI groups (n=3). (B) Representative electron micrographs (8,000×) of myocardial tissue. Yellow arrowheads indicate membrane pores (n=3). (C) Relative protein levels of caspase-1, cleaved caspase-1, NLRP3, and ASC in sham and MI groups (n=6). (D) LDH levels in serum (n=6). Values are presented as means ±SD. * p<0.05, ** p<0.01 relative to MI group.