Table 1.
Gene sequences with their accession numbers and outputs.
| Sequence Name | Accession Number | Function | Output | ||
|---|---|---|---|---|---|
| Mdm4 | JN794077 | Tumor protein p53 pathway | 1 | ||
| BCL9 | KP345733 | Embryonic development | 2 | ||
| ARNT | M69238 | Xenobiotic metabolism | 3 | ||
| ABL2 | DQ084361 | Proliferation | 4 | ||
| MET | NM_001127500 | Embryonic development, organogenesis and wound healing | 5 | ||
| COPS5 | NM_006837 | Regulator in multiple signaling pathways | 6 | ||
| MTDH | NM_178812 | Angiogenesis | 7 | ||
| COX6C | AH006984 | Mitochondrial respiratory chain | 8 | ||
| MYC | NM_002467 | Cell cycle progression, apoptosis and cellular transformation | 9 | ||
| CCND1 | NM_053056 | Proliferation | 10 | ||
| FGF19 | AY358302 | FGF family | 11 | ||
| EEF1A2 | NM_001958 | Enzymatic delivery of aminoacltRNAs to the ribosome | 12 | ||
| TNFRSF14 | NM_003820 | TNF-receptor superfamily | 13 | ||
| CDKN2C | NM_001262 | Cell growth regulator | 14 | ||
| ARID1A | NM_006015 | Regulate transcription | 15 | ||
| TNFAIP3 | NM_001270508 | NF-κB pathway | 16 | ||
| CSMD1 | AY358174 | Tumor suppressor | 17 | ||
| DLC1 | NM_182643 | Human hepatocellular carcinoma | 18 | ||
| SORBS3 | NM_005775 | Migration | 19 | ||
| WRN | AF091214 | Cell division and repairing DNA | 20 | ||
| SH2D4A | NM_022071 | Proliferation | 21 | ||
| PROSC | NM_007198 | Unknown | 22 | ||
| CDKN2A | NM_001195132 | Tumor suppressor by regulating the cell cycle | 23 | ||
| CDKN2B | NM_004936 | Tumor suppressor by regulating the cell cycle | 24 | ||
| PTEN | AH007803 | Tumor suppressor by inhibition of the AKT signaling pathway | 25 | ||
| SPRY2 | NM_005842 | Proliferation | 26 | ||
| BRCA2 | U43746 | Repair damaged DNA | 27 | ||
| RB1 | NM_000321 | Tumor suppressor | 28 | ||
| XPO4 | NM_022459 | Nuclear export | 29 | ||
| SMAD4 | NM_005359 | Proliferation or differentiation | 30 | ||
| HNF1A | HM449088.1 | Encoded protein involved in the regulation of the expression of several liver-specific genes | 31 | ||
| APC | M74088.1 | APC protein is a negative regulator that controls beta-catenin concentrations and interacts with E-cadherin, which are involved in cell adhesion | 32 | ||
| PIK3CA | KF921496.1 | integral part of the PI3K pathway | 33 | ||
| TP53 | NC_000017.11 | Encodes P53 which can activate DNA repair proteins when DNA has sustained damage | 34 | ||
| COL1A1 | NM_000088.3 | Encodes a Janus Kinase protein which has been implicated in signaling by members of the type II cytokine receptor family | 35 | ||
| Sequence Name | Accession Number | Function | Output | ||
| TCS2 | NM_000548.4 | Encodes tumor suppressor and is able to stimulate specific GTPases | 36 | ||
| CTNNB1 | NM_001904.3 | Encodes beta-catenin | 37 | ||
| SMARCA4 | NM_001128849.1 | Encodes protein is part of the large ATP-dependent chromatin remodeling complex, which is required for transcriptional activation of genes normally repressed by chromatin | 38 | ||
| AXIN1 | NM_003502.3 | Encodes a cytoplasmic protein which contains a regulation of G-protein signaling domain | 39 | ||
| CHD1L | NM_004284.5 | Encodes a Protein involved in DNA repair | 40 | ||
| JAK2 | NM_004972.3 | Encodes a Janus Kinase protein which has been implicated in signaling by members of the type II cytokine receptor family | 41 | ||
| BRAF | NM_004333.5 | Encoded protein is involved in sending signals inside cells which are involved in directing cell growth | 42 | ||
| TCS2 | NM_000548.4 | The gene product is believed to be a tumor suppressor and is able to stimulate specific GTPases | 43 | ||
| NFE2L2 | NM_006164.4 | Encodes protein that regulates the expression of antioxidant proteins that protect against oxidative damage triggered by injury and inflammation | 44 | ||
| ARID2 | NM_152641.3 | Encodes PBAF chromatin-remodeling complex which facilitates ligand-dependent transcriptional activation by nuclear receptors | 45 | ||
| ATM | U82828.1 | Encodes a kinase that phosphorylates several key proteins that initiate activation of the DNA damage checkpoint | 46 | ||