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. Author manuscript; available in PMC: 2018 Sep 7.
Published in final edited form as: Processes (Basel). 2018 Apr 25;6(5):42. doi: 10.3390/pr6050042

Figure 3.

Figure 3.

Alignment of RNA-Seq reads to the human genome. Poly(A) selected RNA from two breast cancer cell lines (MCF-7 and MDA-MB-231) were sequenced with an Illumina Hi-Seq to provide high coverage mRNA transcripts. These transcripts were then compared to reference genome (top in red), with mismatches indicating a possible site of editing activity. Here one such site is shown within the red box, with mismatched reads outlined in green. Alignment was generated using ClustalW (http://www.genome.jp/tools-bin/clustalw) [40].