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. 2018 Sep 7;13(9):e0203392. doi: 10.1371/journal.pone.0203392

Fig 4. Progression-free survival (PFS) relationships to the absolute value of involved serum heavy-light chain (isHLC) and the ratio of highly abnormal sHLC (HA-sHLCr).

Fig 4

(A) PFS among patients with absolute values of isHLC <30 g/L (blue, median PFS: 39 mo), 30–50 g/L (green, median PFS: 26 mo), or >50 g/L (red, median PFS: 35 mo). (B) PFS among patients with HA-sHLCr (<0.29 or >73, red; median PFS: 29 mo) vs. those with normal sHLCr (0.29–73, blue; median PFS: 36 mo). (C) PFS among patients with after-treatment absolute values of isHLC <5 g/L (blue, median PFS: 66 mo) vs. ≥5 g/L (red, median PFS: 47 mo), regardless of the response achieved. (D) PFS among patients that achieved partial response (PR) after treatment with absolute values of isHLC <5 g/L (blue, median PFS: Non reached (NR) vs. ≥5 g/L red, median PFS: 28 mo).