Table 1. Pharmacokinetic data for 5 dogs receiving chlorambucil at 4 mg m-2 per day.
Dose (mg m-2) |
Cmax (ng/mL) | Tmax (hours) | t1/2 (hours) | |
---|---|---|---|---|
Dog 1 | 4.76 | 31.32 | 0.50 | 1.57 |
Dog 2 | 3.80 | 4.50 | 0.17 | 3.63 |
Dog 3 | 4.17 | 17.00 | 1.00 | 1.46 |
Dog 4 | 4.39 | 28.20 | 1.00 | 0.86 |
Dog 5 | 4.25 | 21.50 | 1.00 | 0.96 |
Mean (SD) | 4.27 (0.35) |
20.50 (10.55) | 0.73 (0.38) | 1.70 (1.12) |