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. 2018 Jun 25;57(29):4357–4367. doi: 10.1021/acs.biochem.8b00559

Scheme 3. Kinetic Mechanism and Rate-Limiting Steps of PaHisGS (top) and PaATPPRT (bottom) Reactions and the Corresponding Crystal Structures26,29 .

Scheme 3

The second PaHisGS homodimers lie behind the PaHisZ tetramers.