Table 4. Property of discriminative ability of individual scores in predicting in-hospital mortality.
| Score | Cut-off# | Youden Index | Sensitivity (95% CI) | Specificity (95% CI) | +LR (95% CI) | -LR (95% CI) |
|---|---|---|---|---|---|---|
| APACHE II | > 9 | 0.72 | 89.5 (66.9–98.7) | 82.1 (69.6–91.1) | 5.0 (2.8–9.0) | 0.13 (0.03–0.5) |
| APACHE III | > 39 | 0.80 | 94.7 (74.0–99.9) | 85.7 (73.8–93.6) | 6.6 (3.5–12.7) | 0.06 (0.009–0.4) |
| SOFA | > 1 | 0.56 | 89.5 (66.9–98.7) | 66.1 (52.2–78.2) | 2.6 (1.8–3.9) | 0.16 (0.04–0.6) |
| SCORTEN | > 2 | 0.60 | 93.3 (68.1–99.8) | 66.7 (53.3–78.3) | 2.8 (1.9–4.1) | 0.1 (0.01–0.7) |
| KDIGO | > 1 | 0.70 | 73.3 (44.9–92.2) | 85.0 (73.4–92.9) | 4.9 (2.5–9.6) | 0.3 (0.1–0.7) |
+LR, positive likelihood ratio; -LR, negative likelihood ratio; APACHE, Acute Physiology and Chronic Health Evaluation; KDIGO, Kidney Disease Improving Global Outcomes; SCORTEN, severity-of-illness for toxic epidermal necrolysis; SOFA, sequential organ failure assessment score.
# is according to Youden Index.