Fig 3. Protein expression of proteolyic degradation enzymes, IDE, CatD and neprilysin in the liver of non-demented controls (NDC) and Alzheimer’s disease (AD) subjects.

Liver protein expression of the proteolytic degradation enzyme insulin degrading enzyme (IDE) was lower in AD subjects (A); while cathepsin (CatD) levels (B) were higher. Neprilysin was not statistically significantly between the two groups (C). GAPDH was used as a total protein loading control.