Table 3. Risk factors predictive of HAM/TSP in univariate and multivariate regression.
VARIABLES | UNIVARIATE | MULTIVARIATE | ||||||
---|---|---|---|---|---|---|---|---|
B | OR | 95% CI | P | B | OR | 95% CI | P | |
Thoracic SC SUV | -6.904 | 0.001 | 0.001–0.118 | 0.011 | -8.536 | 0.001 | 0.001–0.141 | 0.011 |
CSF ITAC | 0.026 | 1.027 | 1.006–1.047 | 0.024 | 0.032 | 1.033 | 1.004–1.062 | 0.006 |
Female gender | 1.754 | 5.778 | 1.258–26.53 | 0.024 | 0.124 | |||
Plasma IL-6 | 1.514 | 4.545 | 1.005–20.55 | 0.049 | 0.141 | |||
CSF INF-gamma | 0.608 | 1.836 | 1.041–3.238 | 0.036 | 0.323 | |||
CSF IL-8 | 0.165 | 1.179 | 1.014–1.372 | 0.033 | 0.421 | |||
Blood proviral load | 0.004 | 1.004 | 1.000–1.008 | 0.050 | 0.312 |
Multivariate conditional backward stepwise (Wald) model with imput p = 0.100, constant p = 0.048. Adjusted R2 of the multivariate model: 0.654. Hosmer-Lemeshow test, p = 0.297.