Table 1. Summary of mutations rescued by SMT3-Q56K.
Gene | Protein | # of alleles | Mutations |
---|---|---|---|
MOT1 | Negative regulator of TBP | 3 | mot1-399 (Q1587 Stop) |
mot1-517 (G1410R) | |||
mot1-753 (G1300S) | |||
SMT3 | SUMO | 4 | Not sequenced |
AOS1 | SUMO E1 | 1 | aos1-492 (G56S) |
ULP2 | SUMO protease | 4 | ulp2-4 (S108 Stop) |
ulp2-253 (G265D) | |||
ulp2-527 (W532 Stop) | |||
ulp2-63 (W532 Stop) | |||
RPC160 | RNA Pol III subunit | 8 | rpc160-58 (M809I) |
rpc160-85 (G1297D) | |||
rpc160-33 (T379I) | |||
rpc160-419 (A880T) | |||
rpc160-426 (E282K) | |||
rpc160-480 (G1098D) | |||
rpc160-628 (R365K) | |||
rpc160-211 (G606S) | |||
RPC128 | RNA Pol III subunit | 2 | rpc128-202 (A704T) |
rpc128-578 (D501N) | |||
BRF1 | TFIIIB subunit | 1 | brf1-137 (S271L) |
TFC1 | TFIIIC subunit | 1 | tfc1-321 (N255K, Fs) |
(AAC-AAAC, Ins, Fs) | |||
TFC6 | TFIIIC subunit | 1 | tfc6-192 (G391E) |