Table 6.
Behavioural changes in the animals in pilocarpine model of seizures.
Group | % PCS | % SMS | Seizures latency (min) |
% Seizures | SE latency (min) |
Death latency (min) |
% Death |
---|---|---|---|---|---|---|---|
−ve group | 100 | 96.4 | 6.56 ± 0.66 | 96.4 | 13.18 ± 1.48 | 17.0 ± 1.71 | 82 |
C-CL | 100 | 95.9 | 6.16 ± 0.63 | 95.9 | 13.33 ± 1.23 | 17.8 ± 1.68 | 81 |
R-CL | 99.9 | 77.1 | 21.71 ± 2.34 | 40 | 24.71 ± 2.15 | 24.17 ± 2.23 | 68 |
T-CL | 99.7 | 46.7 | 33.17 ± 3.33 | 17.5 | 47.17 ± 3.21 | 51.25 ± 4.13 | 25 |
SE = status epileptics; −ve group = pilocarpine 400 mg/kg, IP, n = 15; C-CL = GMOPF127 mixture, t.d., n = 15; R-CL = Clonazepam of 100 mg/g, 40 mg/kg, orally, n = 15; T-CL = CL-cubogel of 50 mg/g, 40 mg/kg, t.d., n = 15. The results were expressed as the mean ± standard error and percentage (%).