Table 2.

IHC expression analysis of selected genes among three molecular subtypes of ULM

No. cases		MED12 ULM	HMGA2 ULM	FH ULM	MM Controls	p-value*
		25	15	27	40
ER-%	Median (low-high 95% CI)	60 (50.4–60.9)	80.0 (62.8–85.2)	45.0 (29.8–55.5)	70.0 (58.1–74.0)	0.0007
ER-I	Median (low-high 95% CI)	2.0 (1.76–2.24)	3.0 (2.11–2.82)	1.0 (0.61–1.30)	2.0 (1.88–2.43)	0.0001
PR-%	Median (low-high 95% CI)	70.0 (51.2–71.2)	80.0 (56.3–81.0)	90.0 (73.9–89.9)	75.0 (66.0–78.0)	0.0056
PR-I	Median (low-high 95% CI)	2.0 (1.84–2.56)	3.0 (2.18–2.89)	3.0 (2.59–3.03)	2.0 (2.04–2.46)	0.0044
IGF2BP2-I	Median (low-high 95% CI)	1.0 (0.31–0.92	3.0 (1.99–2.81)	1.0 (0.72––1.28)	1.0 (0.58–0.92)	0.0001
pAKT-I	Median (low-high 95% CI)	1.0 (1.20–1.66)	3.0 (2.25–2.95)	1.0 (1.26–1.67)	2.0 (1.48–1.92)	0.0001
pS6-I	Median (low-high 95% CI)	1.0 (1.23–1.68)	3.0 (2.32–2.88)	2.0 (1.35–1.77)	2.0 (1.37–1.84)	0.0001
Ki-67-%	Median (low-high 95% CI)	2.0 (1.98–4.50)	10.0 (5.56–14.04)	1.0 (0.23–2.37)	1.0 (0.57–2.01)	0.0001
P16-%	Median (low-high 95% CI)	5.0 (4.47–12.25)	1.0 (0.01–3.09)	5.0 (4.90–17.10)	1.0 (0.65–2.84)	0.0060

^*One way Anova analysis.