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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Br J Haematol. 2018 Jul 9;182(6):859–869. doi: 10.1111/bjh.15491

Table IV.

Final multivariate analysis of overall survival using Cox model with backward selection

HR (95% CI) Wald test p-value
Initial LDH
 < 2 NL 1
 ≥2 NL 2.86 (1.57–5.20) 0.0006
Time to failure
 ≤6 months 1
 > 6 months 0.59 (0.36–0.97) 0.038
Failure in bone marrow
 No 1
 Yes 2.78 (1.65–4.68) 0.0001

HR, hazard ratio; LDH, lactate dehydrogenase; NL, normal limit.