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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Mol Cell Neurosci. 2018 Mar 24;91:140–150. doi: 10.1016/j.mcn.2018.03.008

Figure 2. Modeling height-related risk-taking in Syngap1 mice.

Figure 2

A) Cliff avoidance task in adult conventional Syngap1 animals. We calculated the fraction of animals remaining on the platform over the course of a ten-minute testing period; chi square, X2(1)= 9.061, p<0.003. B) Modifications to cliff avoidance apparatus made for testing young mice. C) Risk-taking platform with quantifiable risk-taking postures in PND21 mice. D) Top-view heat map showing cumulative location of nose around the platform for each genotype. E) Quantification of risk-taking behaviors. left, number of edge departures during the test; t-test, p<0.001. right, cumulative fraction remaining on the apparatus as animals make their first full departure from the platform; chi square, X2(1)= 8.59, p<0.005.