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. Author manuscript; available in PMC: 2019 Sep 1.
Published in final edited form as: Mol Cell Neurosci. 2018 Mar 24;91:140–150. doi: 10.1016/j.mcn.2018.03.008

Figure 3. Brain volume measurements in Syngap1 mice.

Figure 3

A) Various MRI sections depicting absolute changes in brain volume in Syngap1 Het mice (n=18) relative to Syngap1 WT (n=16) at PND90. Blue color represents significance of reduced volume across brain areas thresholded at 5% FDR. B) Total brain volume in WT and Het mice. Bar graphs and relative data points depicting the absolute volume change in both mutants and wildtypes [t(27.680) = 4.319 p = .0002]; C) Evaluation of total brain volume analyzing male and female separately. Male [t(16) = 4.977, p = .00014]; Female [t(14) = 2.251, p =.041]