Table 2:
Group medians and IQRs of neck vessel total cross-sectional area at baseline, and follow-up in HC (n = 22) and MS (n = 69) groups
| Vessel/Cervical Level | HC BL CSA (mm2) (Median) (IQR) | MS BL CSA (mm2) (Median) (IQR) | BL CSA MS vs HC (P Value) | HC FU CSA (mm2) (Median) (IQR) | MS FU CSA (mm2) (Median) (IQR) | FU CSA MS vs HC (P Value) | HC CSA BL vs FU (P Value) | MS CSA BL vs FU (P Value) | BL-to-FU MS vs HC CSA (P Value) |
|---|---|---|---|---|---|---|---|---|---|
| CCA–ICAs | |||||||||
| C3 | 67.5 (28.1) | 54.5 (28.3) | .298a | 75.6 (30.7) | 57.6 (32.9) | .248a | .223c | .993c | .699e |
| C4 | 73.4 (19.9) | 79.3 (28.2) | .298a | 73.2 (12.9) | 77.5 (27.3) | .535a | .57c | .048c,g | .365e |
| C5 | 69.7 (14.7) | 75.7 (20.9) | .298a | 67.0 (7.9) | 70.9 (23.5) | .248a | .168c | .361c | .365e |
| C6 | 66.7 (10.8) | 71.5 (16.7) | .318a | 66.5 (9.7) | 67.8 (19.4) | .474a | .223c | .222c | .603e |
| C7 | 69.1 (8.9) | 69.7 (19.8) | .795a | 66.3 (7.9) | 66.5 (20.3) | .474a | .030c,g | .005c,g | .36e |
| WV | 68.8 (16.4) | 71.8 (26.2) | .605b | 68.1 (15.8) | 69.0 (26.7) | .632b | .206d | .012d,g | .967f |
| VAs | |||||||||
| C3 | 31.9 (6.5) | 31.7 (6.9) | .597a | 28.7 (11.5) | 30.3 (7.2) | .718a | .070c | .028c,g | .921e |
| C4 | 30.1 (8.5) | 30.0 (5.9) | .597a | 28.8 (10.8) | 29.7 (6.5) | .779a | .288c | .028c,g | .921e |
| C5 | 29.1 (8.0) | 29.4 (6.0) | .597a | 29.4 (10.6) | 29.4 (6.3) | .948a | .570c | .051c | .921e |
| C6 | 28.4 (7.6) | 29.7 (6.9) | .588a | 27.6 (8.4) | 28.9 (7.0) | .718a | .570c | .051c | .921e |
| C7 | 28.4 (9.2) | 29.2 (8.1) | .588a | 27.0 (8.0) | 28.6 (8.0) | .718a | .570c | .028c,g | .92e |
| WV | 29.7 (7.9) | 30.5 (7.5) | .406b | 28.5 (9.8) | 29.6 (7.9) | .377b | .119d | .012d,g | .866f |
| IJVs | |||||||||
| C3 | 100.8 (59.9) | 105.3 (59.7) | .956a | 94.8 (52.9) | 90.6 (60.8) | .970a | .444c | .014c,g | .987e |
| C4 | 111.4 (44.8) | 121.8 (67.9) | .956a | 107.6 (63.9) | 102.8 (74.0) | .970a | .444c | .008c,g | .987e |
| C5 | 117.1 (86.7) | 122.4 (59.8) | .956a | 103.9 (89.3) | 107.9 (71.6) | .970a | .444c | .010c,g | .987e |
| C6 | 116.7 (124.2) | 118.7 (91.6) | .956a | 86.7 (120.0) | 101.4 (86.9) | .970a | .444c | .010c,g | .987e |
| C7 | 116.9 (174.2) | 126.3 (95.4) | .956a | 109.4 (111.6) | 113.2 (90.7) | .970a | .935c | .008c,g | .987e |
| WV | 111.9 (87.0) | 119.5 (73.5) | .790b | 99.3 (76.1) | 103.8 (76.4) | .913b | .424d | .002d,g | .680f |
Note:—BL indicates baseline; FU, follow-up.
Group medians and IQR of neck vessel total CSA at baseline and follow-up are reported for HC and MS at each cervical level and for the WV course. To evaluate CSA differences between HC and MS groups at baseline and at follow-up, an independent-samples Mann-Whitney U test (a) was used at each cervical level, while linear mixed models were used for the WV (b). To evaluate differences between baseline and follow-up within each group, the Wilcoxon signed-rank test (c) was used at each cervical level, while linear mixed models were used for the WV (d). To perform baseline-to-follow-up CSA comparison between groups, linear mixed models were used at each cervical level (e) and for the WV (f). The Benjamini-Hochberg procedure was performed to correct for multiple comparisons.
An α level of .05 was considered significant.