Table 1.
Baseline characteristics of study participants according to the MTNR1B rs10830963 genetic variant
| CC | CG | GG | p value | |
|---|---|---|---|---|
| n=393 | n=273 | n=56 | ||
| Age (years) | 50.8 (9.2) | 51.0 (9.1) | 53.0 (10.3) | 0.24 |
| Sex | 0.72 | |||
| Male | 149 (37.9) | 112 (41.0) | 22 (39.3) | |
| Female | 244 (62.1) | 161 (59.0) | 34 (60.7) | |
| Race or ethnic group | <0.001 | |||
| White | 279 (71.0) | 247 (90.5) | 49 (87.5) | |
| African American | 96 (24.4) | 12 (4.4) | 3 (5.4) | |
| Hispanic or other | 18 (4.6) | 14 (5.1) | 4 (7.1) | |
| Diet group | 0.69 | |||
| Low fat | 198 (50.4) | 134 (49.1) | 31 (55.4) | |
| High fat | 195 (49.6) | 139 (50.2) | 25 (44.6) | |
| Dietary intake per day a | ||||
| Energy (kcal) | 1945 (555) | 2016 (572) | 1884 (448) | 0.36 |
| Protein (%) | 18.0 (3.4) | 18.3 (3.0) | 18.2 (3.2) | 0.77 |
| Fat (%) | 36.9 (5.9) | 37.0 (6.1) | 37.6 (6.3) | 0.85 |
| Carbohydrate (%) | 45.1 (7.8) | 43.8 (7.6) | 44.9 (7.3) | 0.31 |
| Body weight (kg) | 93.7 (15.0) | 92.8 (16.0) | 92.0 (17.5) | 0.66 |
| BMI (kg/m2) | 32.9 (3.8) | 32.3 (3.9) | 32.5 (3.7) | 0.11 |
| WC (cm) | 103.9 (13.0) | 103.2 (13.2) | 103.9 (13.4) | 0.78 |
| Body composition b | ||||
| Total body fat (kg) | 35.3 (8.0) | 34.5 (8.1) | 34.6 (5.6) | 0.62 |
| Total body lean (kg) | 60.8 (12.8) | 60.4 (13.6) | 56.5 (13.1) | 0.26 |
| Total body fat mass (%) | 37.0 (7.1) | 36.6 (6.9) | 38.4 (6.5) | 0.44 |
| Trunk fat (%) | 38.2 (6.2) | 37.5 (6.1) | 38.6 (5.8) | 0.54 |
BMI, Body mass index; WC, Waist circumference Data are expressed as mean (SD) or n (%)
a
Data were available for 370 individuals (CC n=208, CG n=133, GG n=29)
b
Data were available for 382 individuals (CC n=204, CG n=149, GG n=29)