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. 2018 Sep 7;8:13428. doi: 10.1038/s41598-018-31504-4

Figure 2.

Figure 2

HMGB1 in plasma and sputum in relation to inflammation and disease severity. Correlation between plasma HMGB1 and plasma IL-8 (A) or Pneumonia Severity Index (PSI) risk class I (n = 9), II (n = 34), III (n = 30), IV (n = 32) and V (n = 6) (B) in 111 patients with bacterial community-acquired pneumonia (CAP). Correlation between sputum HMGB1 and plasma IL-8 (C) or PSI risk class I (n = 3), II (n = 9), III (n = 13), IV (n = 15) and V (n = 2) (D) in 42 patients with bacterial CAP. In the box plots, the open circles and stars represent outliers and extreme outliers, with patient study number.