Table 1.
Characteristics of the patient cohort.
| Patient characteristics | All patients (n = 111) | All patients with an available sputum sample (n = 42) | All patients with an available sputum sample and pneumococcal aetiology (n = 19) |
|---|---|---|---|
| Female gender, n (%) | 62 (56) | 22 (52) | 7 (37) |
| Age, median years (range) | 67 (18–93) | 67 (18–93) | 67 (39–89) |
| Comorbiditya, n (%) | 50 (45) | 22 (52) | 12 (63) |
| Chronic obstructive pulmonary disease, n (%) | 19 (17) | 12 (29) | 8 (42) |
| Smoking, n (%) | 53 (48) | 26 (62) | 16 (84) |
| C-reactive protein, median mg/L (range) | 214 (9–773) | 214 (9–610) | 253 (9–610) |
| Plasma interleukin-8, median pg/mL (range) | 32 (0–2009) | 33 (2–1516) | 46 (2–1516) |
| PaO2/FiO2 ratio, median (range) | 290 (135–555) | 290 (135–458) | 300 (135–405) |
| Severe pneumonia (ATS/IDSA criteria), n (%) | 15 (14) | 5 (12) | 3 (16) |
| Pneumonia Severity Index risk class IV-V, n (%) | 38 (34) | 17 (40) | 8 (42) |
| Sepsis (Sepsis-3 criteria), n (%) | 67 (60) | 29 (69) | 13 (68) |
| Intensive care unit admission, n (%) | 9 (8) | 4 (10) | 2 (11) |
| 30-day mortality, n (%) | 3 (3) | 1 (2) | 0 (0) |
aMalignancy, liver disease, renal disease, chronic obstructive pulmonary disease, heart disease, history of stroke, diabetes.