Table 3.

Clinical parameters for each week of proton therapy

Parameters	Week 1	Week 2	Week 3	Week 4	p value* for mean differences during study period
Mean arterial blood pressure during procedure, mmHg	61.6 ± 9.9	61.0 ± 10.5	61.0 ± 9.9	62.9 ± 10.5	0.655
Mean heart rate during procedure, bpm	90.3 ± 13.9	89.0 ± 13.0	89.6 ± 14.8	86.1 ± 14.5	0.496
Sedation time, min	32.6 ± 17.2	30.2 ± 14.7	28.4 ± 12.6	25.4 ± 12.5	0.361
Procedure time, min	25.3 ± 16.7	23.3 ± 14.4	21.2 ± 12.6	18.7 ± 12.3	0.217
PACU stay time, min	68.3 ± 13.5	70.3 ± 18.6	71.7 ± 18.3	67.8 ± 14.7	0.387

Data are presented as mean ± standard deviations. PACU, post-anesthesia care unit. ^*Analysis of variance with repeated measures using the mixed model