Table 5.
Variants interacting with hours of fasting or time of day in fat and skin regulate expression of fasting or time of day associated genes
| Tissue | Exposure | Gene | SNP | Chr | P | FWER |
|---|---|---|---|---|---|---|
| Fat | Fasting | ACTA2 | rs813782 | 10 | 9.8E-06 | 1.0E-02 |
| Fat | Fasting | CBFA2T3 | rs12921348 | 16 | 5.6E-05 | 3.4E-02 |
| Fat | Fasting | FRMD4A | rs10906711 | 10 | 2.9E-05 | 4.3E-02 |
| Fat | Fasting | HK2 | rs11690080 | 2 | 3.7E-05 | 3.0E-02 |
| Fat | Fasting | KIAA0182 | rs56377278 | 16 | 4.9E-05 | 4.7E-02 |
| Fat | Fasting | KLHL25 | rs11854452 | 15 | 1.9E-05 | 1.8E-02 |
| Fat | Fasting | MBD5 | rs13016227 | 2 | 3.0E-05 | 1.0E-02 |
| Fat | Fasting | PLXND1 | rs2403343 | 3 | 1.0E-04 | 2.9E-02 |
| Fat | Fasting | PPFIBP1 | rs405394 | 12 | 6.0E-05 | 4.8E-02 |
| Fat | Fasting | RP11-399O19 | rs813782 | 10 | 7.6E-05 | 4.4E-02 |
| Fat | Fasting | STARD13 | rs9591423 | 13 | 8.4E-05 | 4.7E-02 |
| Fat | Fasting | THRA | rs11651987 | 17 | 2.4E-05 | 1.3E-02 |
| Fat | TOD | FZD10 | rs11061011 | 12 | 4.0E-05 | 3.4E-02 |
| Skin | TOD | HR | rs10110714 | 8 | 7.6E-05 | 4.8E-02 |