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. 2018 Sep 4;13:5059–5073. doi: 10.2147/IJN.S172906

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© 2018 Sudirman et al. This work is published and licensed by Dove Medical Press Limited

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Thickness of seminiferous tubule in STZ-induced diabetic rats: (A) Con, (B) DM, (C) Nano-PAC5, and (D) Met.

Notes: The testis sections were stained with H&E. The yellow arrow indicates the changes in the seminiferous tubule.

Abbreviations: STZ, streptozotocin; Con, control; DM, diabetes mellitus; Nano-PAC5, diabetes+20 mg/kg per day Nano-PAC; Met, diabetes+300 mg/kg per day metformin; Nano-PAC, PAC encapsulated in silica–chitosan nanoparticles; PAC, petri dish-cultured Antrodia cinnamomea.