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. 2018 Sep 4;12:2715–2730. doi: 10.2147/DDDT.S176349

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© 2018 Wei et al. This work is published and licensed by Dove Medical Press Limited

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βE₂ administration protects against blue LED-induced RD. Female OVX rats were treated with βE₂ (10 µM) via IVI for 4 h and then exposed to 3000 lux blue LED for 2 h. The functional and morphological changes were determined via ERG assays.

Notes: (A) and H&E staining (C), respectively. The statistical analysis of the mean amplitudes of the a- and b-waves (B).ONL thickness (D) was measured from the optic nerve head to the superior and inferior retinae in the above groups. The data represent the mean ± SEM; n=6 (eye samples in each group). ^*P<0.05 vs. control; ^#P<0.05 vs. blue LED.

Abbreviations: βE₂, 17β-estradiol; LED, light-emitting diode; ONL, outer nuclear layer.

βE₂ administration protects against blue LED-induced RD. Female OVX rats were treated with βE₂ (10 µM) via IVI for 4 h and then exposed to 3000 lux blue LED for 2 h. The functional and morphological changes were determined via ERG assays.

Notes: (A) and H&E staining (C), respectively. The statistical analysis of the mean amplitudes of the a- and b-waves (B).ONL thickness (D) was measured from the optic nerve head to the superior and inferior retinae in the above groups. The data represent the mean ± SEM; n=6 (eye samples in each group). ^*P<0.05 vs. control; ^#P<0.05 vs. blue LED.

Abbreviations: βE₂, 17β-estradiol; LED, light-emitting diode; ONL, outer nuclear layer.