Table 5.
Logistic regression analysis identifying predictors for anastomotic leakage
| Characteristics | Univariate | Multivariate | ||||
| OR | 95% CI | P values | OR | 95% CI | P values | |
| Age >60 years | 1.956 | 1.017 to 3.762 | 0.044 | 1.476 | 0.797 to 2.732 | 0.215 |
| Obesity | 1.686 | 0.931 to 3.053 | 0.084 | 1.320 | 0.714 to 2.440 | 0.376 |
| Alcohol history | 1.768 | 0.966 to 3.237 | 0.065 | 1.281 | 0.718 to 2.284 | 0.402 |
| Smoking history | 1.835 | 0.954 to 3.531 | 0.069 | 1.456 | 0.525 to 4.038 | 0.067 |
| Comorbidities | ||||||
| Diabetes mellitus | 2.207 | 1.128 to 4.317 | 0.021 | 2.000 | 1.008 to 3.968 | 0.047 |
| Coronary artery disease | 1.894 | 0.915 to 3.919 | 0.085 | 1.482 | 0.682 to 3.221 | 0.321 |
| Peptic ulcer disease | 1.973 | 0.859 to 4.535 | 0.109 | 1.420 | 0.565 to 3.567 | 0.456 |
| Tumour location (%) | ||||||
| Junction | 1 | Reference | 0.044 | 1 | Reference | 0.154 |
| Distal oesophagus | 1.876 | 1.016 to 3.462 | 1.582 | 0.842 to 2.970 | ||
| Anastomotic level (%) | ||||||
| IOA | 1 | Reference | 0.062 | 1 | Reference | 0.110 |
| COA | 1.753 | 0.974 to 3.155 | 1.622 | 0.897 to 2.934 | ||
| Surgical procedure,% | ||||||
| Open | 1 | Reference | 0.032 | 1 | Reference | 0.049 |
| Minimally invasive | 1.863 | 1.055 to 3.290 | 1.770 | 1.003 to 3.125 | ||
| Anastomotic mode, % | ||||||
| Semimechanical | 1 | Reference | 0.024 | 1 | Reference | 0.048 |
| Stapled | 2.174 | 1.070 to 4.416 | 1.821 | 0.854 to 3.880 | ||
| Handsewn | 2.284 | 1.118 to 4.664 | 2.271 | 1.055 to 4.887 | ||
COA, cervical oesophagogastric anastomosis; IOA, intrathoracic oesophagogastric anastomosis.