Figure 1.

Plasmodium vivax infection induces increased proportion of regulatory T cells (Treg). A, Representative density plots showing the gating strategy. Treg were analyzed after gating live cells and based on the expression of CD3, CD4, CD25, forkhead box P3 (Foxp3), and excluding those bearing CD127. B, Peripheral blood mononuclear cells from malaria patients were analyzed ex vivo during acute infection with P. vivax before treatment (BT; ●; n = 14) and 30–45 days after treatment (AT; ○; n = 14) and frequencies are represented as dispersion symbols. Lines represent median values in each group. * P < .05, using the Wilcoxon test when comparing BT versus AT. Abbreviation: FSC, forward scatter.