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. 2018 Aug 9;3(15):e121468. doi: 10.1172/jci.insight.121468

Figure 1. Airway surface liquid pH is abnormally acidic in cystic fibrosis neonates and increases by 3 months of age.

Figure 1

(A) The non-CF group includes 4 neonates without cystic fibrosis transmembrane conductance regulator (CFTR) mutations and 41 neonates heterozygous for a CFTR mutation. The cystic fibrosis (CF) group includes 11 neonates. Bars and whiskers indicate mean ± SD. *P = 0.01 by Mann-Whitney test. (B) Airway surface liquid (ASL) pH in CF neonates (n = 11) measured at birth and at 3-month intervals. Data points and connecting lines represent values for individuals. We compared values at birth and at 6 months, a time point when we had data for 10 of the participants. *P = 0.025 by Wilcoxon matched-pairs signed-rank test.