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. 2018 Aug 9;3(15):e98720. doi: 10.1172/jci.insight.98720

Figure 1. Dapagliflozin induces glycosuria and natriuresis, and limits proteinuria in mice with protein overload.

Figure 1

(A–D) Mice were placed in metabolic cages and 24-hour urine was collected for evaluation of glucose excretion (A, n = 8–12), diuresis (B, n = 8–12), sodium excretion (C, n = 8–12), and urinary protein to creatinine ratio (D, n = 8–12) on day 23 after starting BSA injections. Data are the mean ± SEM and were analyzed by ANOVA with Tukey’s post hoc test. DAPA, dapagliflozin; ACEi, ACE inhibitor.