Table 5.

Median degrees of vertices identified by each method on different interaction networks, with methods sorted from smallest to largest degree

Methods	HINT +  HI degree	iRefIndex degree	ReactomeFI degree
NetSig	27	54	46
Hierarchical HotNet	33.5	106	48
MutSig	29	95	90
HotNet2	32	92	95.5
heinz	40.5	118	104.5
DNmax	56	154	121
DNsum	53	170	124
Degree-biased MutSig	54	175	128