Table 5.
Change in Y | C1: direct effect of X on Y before mediation | C2: direct effect of X on Y after mediation | A: indirect effect of X on Y mediated via M | B: direct effect of M on Y adjusted for X | ||||||
---|---|---|---|---|---|---|---|---|---|---|
R 2 | p | Unstandardized effect size | 95% CI | Unstandardized effect size | 95% CI | Unstandardized effect size | 95% CI | Unstandardized effect size | 95% CI | |
Total sample n = 69 | ||||||||||
Model A | ||||||||||
X = MCCB | 0.6241 | 0.0000 | −0.0065 | −0.0345, 0.0215 | 0.0307 | − 0.0057, 0.0671 | 0.0372 | 0.0129, 0.0663 | 1.8406 | 1.3673, 2.3138 |
M = change D-3 mean | ||||||||||
Model B | ||||||||||
X = MCCB | 0.6044 | 0.0000 | 0.0121 | 0.0019, 0.0223 | 0.0202 | 0.0064, 0.0340 | 0.0081 | −0.0020, 0.0168 | 0.2637 | 0.1959, 0.3316 |
M = change HCR-C | ||||||||||
Less than 5 years n = 35 | ||||||||||
Model A | ||||||||||
X = MCCB | 0.6748 | 0.0000 | −0.0338 | −0.0758, 0.0081 | 0.0213 | −0.0312, 0.0738 | 0.0551 | 0.0239, 0.0911 | 1.8597 | 1.1937, 2.5257 |
M = change D-3 mean | ||||||||||
Model B | ||||||||||
X = MCCB | 0.6768 | 0.0000 | 0.0237 | 0.0092, 0.0382 | 0.0296 | 0.0093, 0.0500 | 0.0059 | −0.0075, 0.0199 | 0.2797 | 0.1795, 0.3799 |
M = change HCR-C | ||||||||||
More than 5 years n = 34 | ||||||||||
Model A | ||||||||||
X = MCCB | 0.6503 | 0.0000 | 0.0240 | −0.0146, 0.0626 | 0.0419 | −0.0144, 0.0981 | 0.0179 | −0.0211, 0.0744 | 2.099 | 1.3878, 2.8104 |
M = change D-3 mean | ||||||||||
Model B | ||||||||||
X = MCCB | 0.6315 | 0.0000 | −0.0026 | −0.0167, 0.0015 | 0.0085 | −0.0115, 0.0285 | 0.0111 | −0.0018, 0.0260 | 0.2653 | 0.1754, 0.3551 |
M = change HCR-C |
Note: CI Confidence interval, MCCB MATRICS consensus cognitive battery, D-3 DUNDRUM-3 Programme Completion Scale mean total score, HCR-C History-Clinical-Risk Management-20 clinical items. In Model A the outcome variable (Y) was change in HCR-20 clinical items during the study. In Model B the outcome variable (Y) was change in DUNDRUM-3 Programme Completion Scale mean total score during the study. X, independent variable; M, mediator variable. All models were controlled for HCR-20 clinical baseline scores and DUNDRUM-3 mean total score at baseline
Model A: Y = HCR-20 clinical score change over four years. Model B: Y = DUNDRUM-3 mean total score change over four years; Results in bold are statistically significant