Table 2.
Right-heart catheterization and pulmonary function data of patients studied.
| Group A (PHA) | Group B (COPD) | Group C (HF) | p | |
|---|---|---|---|---|
| Mean PAP (mm Hg) | 35.5 (8.3) | 38.2 (8.3) | 59.3 (24) | 0.011 |
| 32.5 (28-53) | 37 (23-47) | 65 (33-80) | ||
| Systolic PAP (mm Hg) | 72.7 (21.1) | 81.7 (22.3) | 101.6 (18.9) | 0.158 |
| 70 (48-105) | 83 (50-113) | 110 (80-115) | ||
| CI (l/min) | 2.98 (0.88) | 2.89 (0.79) | 3.33 (0.57) | 0.710 |
| 2.98 (2-5) | 2.8 (1-4) | 3 (3-4) | ||
| Pulmonary capillary wedge pressure (mm Hg) | 13 (4.6) | 14.5 (4.4) | 16 (1.4) | 0.598 |
| 13 (8-22) | 14 (10-22) | 15 (17-21) | ||
| Pulmonary vascular resistance (WU) | 4.7 (2.2) | 5.1(3.8) | 4.8 (1.8) | 0.478 |
| 5.7 (1.8-8.3) | 3.6(1.7-11.3) | 5 (1.8-10) | ||
| Right atrial pressure (mm Hg) | 8.5 (3.6) | 10.2 (2.1) | 9.5 (2.2) | 0.256 |
| 9 (2-13) | 9 (8-13) | 9 (5-16) | ||
| FEV1 (L) | 1.9 (8.85) | 1.5 (0.43) | 1.13 (0.27) | 0.197 |
| 1.7 (1-3.5) | 1.5 (0.79-1.9) | 1 (0.9-1.43) | ||
| FEV1 (%predicted) | 76.7 (17.2) | 58.5 (15.9) | 57.3 (4.5) | 0.071 |
| 81 (55-105) | 65 (31-74) | 57 (53-62) | ||
| FVC (L) | 2.55 (1.1) | 2.9 (1) | 1.4 (045) | 0.158 |
| 2.4 (1.1-4.8) | 2.8 (1.3-4.4) | 1.3 (1-1.9) | ||
| FVC (% predicted) | 82.5 (21.5) | 82.8 (19.4) | 59.6 (7.6) | 0.195 |
| 85 (50-118) | 76 (57-120) | 58 (53-68) | ||
| FEV1/FVC | 74.3 (12.4) | 54.6 (11.8) | 79.6 (16) | 0.007 |
| 73 (53-93) | 54 (35-71) | 73 (68-98) | ||
| DLCO (%predicted) | 37.7 (12.4) | 41.4 (13.6) | 71.6 (7.6) | 0.003 |
| 36 (24-59) | 44 (23-63) | 70 (65-80) | ||
| 6MWD (meters) | 336 (140.3) | 355.3 (153) | 278.3 (158.5) | 0.881 |
| 299(160-497) | 391(100-520) | 207(100-520) |
Data reported as mean (standard deviation) and median (minimum-maximum).
PAP: pulmonary artery pressure; CI: cardiac index; WU: wood units; FEV1: forced expiratory volume in 1 second; FVC: forced vital capacity; DLCO: carbon monoxide diffusion; 6MWD: six-minute walking distance; n.s.: not significant; and p: p value among the groups studied (ANOVA)