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. Author manuscript; available in PMC: 2019 Oct 1.
Published in final edited form as: Matrix Biol. 2018 Mar 9;71-72:161–173. doi: 10.1016/j.matbio.2018.02.023

Figure 4. COMP and fibrosis.

Figure 4

COMP upregulates TGFβ stimulating additional COMP expression. COMP assists in type I collagen secretion which results in stiffening of the ECM, an important component in fibrosis pathology.