Figure 4.

Results of HP1α-dinucleosome molecular simulations in which one CD is bound on the trimethylated H3K and the other CD is free. (A) Statistics of the distances between the free CD and unmethylated H3K9s are shown. One CD is bound on the “A-proximal H3K9.” The red arrows show 6.6 Ǻ, corresponding to the distance at the complex crystal structure of the CD with an H3K9-trimethylated H3 tail fragment. (B) The case of “A-distal H3K9” (bottom) is shown. (C) The number of occurrences in which the distance was below 16.5 Ǻ is given. Results with larger and smaller cutoffs are given in Fig. S12. To see this figure in color, go online.