Figure 6.

Tumor growth in response to supernatants from NDV-infected lung cancer cells. A. A549 and H460 cells were injected subcutaneously into the right flanks of mice to establish tumors. When tumors reached approximately 200 mm³, mice received an intratumoral injection of either PBS, the concentrated cell-free supernatants of NDV/FMW (50 μl), NDV or inactivated NDV every three days. Tumor volumes were measured at 5-day intervals for 40 days after injections and expressed as the Mean ± SD (n = 10) and represented as tumor volume-time curves to show any differences in tumor regression (*P<0.05, **P<0.01). B. Immunohistochemistry assay for expressions of CRT protein in four groups of mice model, arrowheads indicate positive area. Scale bar = 50 μm.