Table 2.
The correlation between miR-34a expression and clinical features from TCGA data
Clinicopathological features | Terms | n | Mean ± SD | p-value |
---|---|---|---|---|
Unpaired tissue | Normal | 44 | 6.86±0.73 | 0.367 |
HNSCC | 485 | 6.74±0.82 | ||
Gender | Male | 381 | 6.79±0.81 | 0.120 |
Female | 148 | 6.67±0.81 | ||
Age | <60 | 224 | 6.79±0.80 | 0.448 |
≥60 | 304 | 6.73±0.82 | ||
Lymphovascular invasion | No | 236 | 6.73±0.81 | 0.976 |
Yes | 119 | 6.73±0.71 | ||
Pathologic grade | G1-G2 | 368 | 6.82±0.81 | 0.013 |
G3-G4 | 139 | 6.62±0.82 | ||
Clinical grade | I-II | 126 | 6.79±0.81 | 0.620 |
III-IV | 389 | 6.75±0.81 | ||
T stage | T1-T2 | 189 | 6.72±0.81 | 0.434 |
T3-T4 | 325 | 6.78±0.80 | ||
N stage | N0 | 253 | 6.80±0.78 | 0.319 |
N1-N3 | 254 | 6.73±0.84 | ||
M stage | M0 | 504 | 6.77±0.80 | 0.260 |
M1 | 4 | 6.31±1.18 | ||
Recurrence | No | 329 | 6.72±0.79 | 0.093 |
Yes | 115 | 6.87±0.84 | ||
Alcohol | No | 173 | 6.79±0.80 | 0.499 |
Yes | 345 | 6.73±0.82 |
Notes: HNSCC, Head and neck squamous cell carcinoma; T stage, size or direct extent of the primary tumor; N stage, degree of spread to regional lymph nodes; M stage, presence of distant metastasis; SD, standard deviation.